LocalFold

LocalFold - Local Folding of RNA

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LocalFold is a modification of the RNAplfold local folding algorithm. It only considers base-pairs centered within a window such that $(i,j)$ are not located within the first and last positions of the windows.

Download and Installation

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Latest Release

• LocalFold 1.0

System Requirements

• LocalFold runs on recent Linux systems.
• Requires a recent installation of the Vienna RNA package.

Publication

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Sita J. Lange, Daniel Maticzka, Mathias Möhl, Joshua N. Gagnon, Chris M. Brown, and Rolf Backofen Global or local? Predicting secondary structure and accessibility in mRNAs